22 Road is the easiest way to experience the uranium mining history and abundant scenic splendor in this unique landscape of western Colorado. The area was mined from around 1910 through the 1980s, producing over 70% of the uranium ever found in Colorado. Beginning from the southeastern trailhead along Highway 90, the trail begins as a gravel road passing two out-and-back campsites tucked up near the red sandstone cliffs. Continuing up Sawtooth Ridge, the scenery becomes increasingly expansive above the valley and at a couple of epic campsites on the cliff. Once on top of the mesa, you can stop at an old mine site with an outbuilding and a large mine tower. The trail winds a long distance across the boulder-strewn mesa, gradually descending to the Department of Energy's uranium waste disposal site. The area is fenced off and clearly marked with radioactive signage. The final descent is along the narrow ledge above Hieroglyphic Canyon, eventually ending at Highway 141 along the San Miguel River. The entire 18-mile trail can be completed in 2WD vehicles with durable tires and high ground clearance. Camping is sporadic along the route, with the best being near Highway 90 trailhead and Sawtooth Ridge.