Owens River Road is a well-maintained dirt road that travels through the Inyo National Forest., and does not require high clearance or 4x4. Any car should be able to handle this trail.
The trail's eastern section is very arid and desolate, symbolic of the landscape of the Eastern Sierras. You're surrounded by the White Mountains to the east and the Sierra Nevada Mountains to the west. You can see the unique formation of the Minaret Peaks to the west and the Mammoth Mountain Ski Resort. Along the trail, the terrain is mostly dry brush and shrubs, and there is volcanic igneous rock along sections to the east of the trail.
This road is part of an intricate trail system that offers many offshoots from the main road that goes into Little Antelope Valley and deeper into the Inyo National Forest. It is BLM land, so dispersed camping is available, but nothing directly on the main trail. The only designated campground is Big Springs at the trail's west end, but it is closed seasonally. Be sure to check if it's open before you go.